A full range of treatment options is available for children with acute or chronic lymphocytic and myelogenous leukemia, including chemotherapy, stem cell transplantation and radiation therapy. Oncology physicians and nurses offer and implement the treatment plan adequate for each child based on the type of leukemia and certain prognostic factors. Children with Hodgkin's disease and non-Hodgkin's lymphoma (NHL) are thoroughly evaluated and promptly treated according to the specific subtype and stage of the disease. They are supported by a team of psychologists, social workers and other specialized professionals who provide compassionate "total care" for the child and family.
Soft Tissue and Solid Tumors
At Children's Hospital, pediatric experts treat a variety of tumors including neuroblastoma, tumors of the central nervous system (brain and spine), soft tissue sarcoma, bone sarcoma, retinoblastoma and Wilms tumor. The Center for Cancer and Blood Disorders is represented by the following medical and surgical disciplines: pediatric oncologic surgery, pediatric neurosurgery, pediatric neuro-oncology, genitourinary oncologic surgery, orthopedic oncologic surgery, pediatric ocular surgery, radiation oncology and pediatric pathology. Members of our medical team are highly skilled individuals dedicated to providing the latest innovative treatments to our young patients.
Stem Cell Transplant Program
Hematopoietic stem cell transplantation (HSCT) has become an alternative approach in the treatment of malignant diseases for many patients. For some diseases, the five-year survival rate surpasses that of chemotherapy alone. The list of diseases for which hematopoietic stem cell transplantation has been considered grows almost daily. Hematopoietic stem cell transplantation allows administration of cytoreductive therapy with curative intent, without regard for the lethal effects to the marrow of this treatment regimen. The sources of stem cells are bone marrow, peripheral blood stem cells mobilized by growth factors or chemotherapy, and cord blood.
The Children's Hospital hematopoietic stem cell transplant program began in January 1989. From January 1989 to December 2014, 337 transplants were performed. Of those performed, 220 were allogeneic and 117 were autologous. By far, the most common conditions for which HSCT has been carried out are hematologic malignancies, e.g., acute leukemia.
Diseases such as leukemia are treated here at Children's Hospital, New Orleans with the same protocols as those of the 240 Children's Oncology Group (COG) institutions (e.g. St. Jude, MD Anderson, Johns Hopkins) adopted throughout the nation. COG has recognized Children's Hospital as the only hematopoietic stem cell transplant site in Louisiana for COG protocol studies.
A multidisciplinary team of physicians, nurses, social workers, nutritionists, pharmacists, physical therapists, psychologists and blood bank personnel is available, with experience and commitment to the clinical practice and basic science of hematopoietic stem cell transplantation.
In July 2000, Children's Hospital, led by Dr. Lolie Yu, became accredited by the National Marrow Donor Program® (NMDP) as a transplant center. Through the NMDP, Children's Hospital has access to the largest worldwide registry of hematopoietic stem cell donors. This affiliation provides patients with the best chance of finding a suitable donor for transplantation. Children's Hospital, in collaboration with LSUHSC, is also an approved COG hematopoietic stem cell transplant center with Dr. Yu as the principal investigator. Our HSOT program is also affiliated with the PBMTC and the BMT- CTN network.
For more information regarding the hematopoietic stem cell transplant center at Children's Hospital, please contact the Hematology/Oncology office or Dr. Lolie Yu at (504) 896-9740.
Children’s Oncology Group
The Children's Oncology Group (COG) is a National Cancer Institute (NCI) -sponsored cooperative group of individuals and institutions dedicated to treating cancer among children and adolescents. COG's purpose is to:
- improve the diagnosis and management of children and adolescents with cancer, with the aim of curing every newly diagnosed patient;
- investigate the etiology, pathology and pathophysiology of childhood cancer;
- assure that every child with cancer achieves the highest quality of life during and following treatment;
- expeditiously disseminate knowledge of these objectives in all appropriate media.
Children's Hospital and the LSUHSC/Stanley S. Scott Cancer Center have been members of COG for almost 20 years. This allows the LSUHSC/Children's Hospital Minority NCI Oncology Research Program (NCORP) to offer innovative and up-to-date clinical trials as part of the NCI-sponsored COG site.